Fig. 4From: Decreased testosterone levels after caponization leads to abdominal fat deposition in chickensEnrichment of candidate pathways related to lipid metabolism and verification of related genes a The nine enriched pathways were screened based on 872 known DEGs. KEGG pathway enrichment analysis was performed using KOBAS 2.0. The enriched pathways were identified using a hypergeometric test from the R packages (Pā<ā0.1, FDR-adjusted), and pathways with fewer than three known chicken genes were discarded. b The changes in expression of six representative genes involved in the PPAR signaling pathway. The mRNA levels of RXRG, FADS2, FABP7, and SCD, which promote lipid deposition, were significantly up-regulated in AF tissues of capons compared with sham-operated control chickens 14 wk. after caponization. FABP3 and APOA1 mRNA levels, genes involved in inhibition of lipid deposition, were significantly down-regulated. Data are means Ā± SEM, nā=ā6. *Pā<ā0.05; **Pā<ā0.01Back to article page