Fig. 3

IsomiR profile of colorectal tissue. a miRNA reads among total mappable small RNA reads. b Canonical form and other isomiR among total miRNA reads. c Addition, deletion and variation forms among all 3′ isomiRs. d Template and non-template forms of 3′ addition form. e Additional nucleotide pattern of all 3′ addition form. f Additional nucleotide pattern of non-template 3′ addition form. g Polymorphic change nucleotide pattern. h Polymorphic change frequency based on nucleotide position as a percentage of total incidence. i Correlation in reads between the most abundant forms and canonical forms of each miRNA. Dots aligned on the diagonal line represent miRNAs whose canonical forms are also the most abundant forms. Otherwise, dots left to the diagonal line represent miRNAs with the most abundant forms being isomiRs. j miRNAs with highest ratios between the most abundant form reads to canonical form reads