Fig. 3
From: When pitch adds to volume: coregulation of transcript diversity predicts gene function
Association between the tissue vulnerability score of AD (Delta BI-III) and enrichment of APP co-splicing, and multiple enrichment in APP epistasis. a Box plots (box: 3rd, 2nd and 1st quartiles, whiskers: outlier fences of 1.5 interquartile range) representing the distributions of Delta BI-III for pathways with no significant enrichment in APP co-splicing (No APP-spl) and for pathways with significant enrichment (APP-spl), for GTEx data. The difference between means (beta) and P-value are reported at the bottom. b Similar plot to (a) for BRAINEAC data. c Dose-response relationship between tissue vulnerability and multiple enrichment in APP epistasis. Each dot is a pathway. The x axis shows the number of genome-wide interaction analyses (GWIAs), from 27 SNPs in APP, in which a pathway was found significantly enriched