Fig. 4

Heat map and Cluster analysis showing the numbers of differentially expressed miRNAs after chlamydia infection and reinfection. a. Heat map showed that there is a difference in miRNA expression profile 1 week after chlamydia infection and reinfection. R script was used to create the heatmap for each set of sample comparison. b. Heat map showed that there is a difference in miRNA expression profile 2 weeks after chlamydia infection and reinfection. R script was used to create the heatmap for each set of sample comparison. c. Heat map showed that there is a difference in miRNA expression profile 4 weeks after chlamydia infection and reinfection. R script was used to create the heatmap for each set of sample comparison. d. Heat map showed that there is a difference in miRNA expression profile 8 weeks after chlamydia infection and reinfection. R script was used to create the heatmap for each set of sample comparison. e. Venn diagram of differentially expressed miRNAs after chlamydia infection. Figure compares the differentially expressed microRNAs 1, 2, 4 and 8 weeks after infection. The numbers in the Venn diagram represents the number of distinct and common microRNAs in the different weeks of infection. There were no common microRNAs expressed in all weeks of infection. p-values here were adjusted by false discovery rate. f. Venn diagram of differentially expressed miRNAs after chlamydia reinfection. Figure compares the differentially expressed microRNAs 1, 2, 4 and 8 weeks after infection. The numbers in the Venn diagram represents the number of distinct and common microRNAs in the different weeks of infection. There were no common microRNAs expressed in all weeks of infection. p-values here were adjusted by false discovery rate. g. Venn Diagram comparing miRNAs expressed during chlamydia infection and reinfection. Figure compares all the differentially expressed microRNAs in chlamydia infection and reinfection. The numbers in the Venn diagram represents the number of distinct and common microRNAs. There were 10 common microRNAs expressed in both chlamydia infection and reinfection. p-values here were adjusted by false discovery rate