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Fig. 7 | BMC Genomics

Fig. 7

From: PLAIDOH: a novel method for functional prediction of long non-coding RNAs identifies cancer-specific LncRNA activities

Fig. 7

PLAIDOH ranks lncRNAs using biological and experimental data from RNA binding protein interaction. a Interaction matrix of lncRNAs and RNA Binding Proteins. Binding events of concordantly localized lncRNAs and RBPs are colored by subcellular localization to the nucleus (blue), cytoplasm (red) or both nucleus and cytoplasm (purple). Discordantly-localized interactions are colored grey. No evidence of binding is white. b Plot shows lncRNA expression versus RBP binding-site density per kilobase of RNA transcript for each lncRNA/RBP interaction shown in panel a. Data point size is scaled to RBP expression level and subcellular localization interactions are colored to match panel a. Labeled dots highlight previously published and validated binding of RBP/lncRNA pairs

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