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Fig. 2 | BMC Genomics

Fig. 2

From: Proteome profiling of triple negative breast cancer cells overexpressing NOD1 and NOD2 receptors unveils molecular signatures of malignant cell proliferation

Fig. 2

Heatmaps showing clustering of differentially expressed proteins found in NOD1 (HS578T/NOD1) (a) and NOD2 (HS578T/NOD2) (b) experimental groups. Pearson clustering for rows and columns was carried out according to the log2-transformed intensity values (calculated by MaxQuant software) for each of three replicates (R) of unmodified HS578T cells (P), HS578T/NOD1 (NOD1) and HS578T/NOD2 (NOD2) groups in MORPHEUS (Versatile matrix visualization and analysis software; https://software.broadinstitute.org/morpheus) [47]. Rows are Identified by Entrez gene names. Intensities are shown by a color range, from red (row max) to white (row average) and blue (row minimum). c Venn diagram showing the distribution of differentially regulated proteins found in NOD1 (HS578T/NOD1; Blue) and NOD2 (HS578T/NOD2; Red) groups, generated in Venny 2.1 (http://bioinfogp.cnb.csic.es/tools/venny) [137]. Circles in scale to group size

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