Fig. 2

LINC01420 knockdown revealed activation of A375 cells migration, but does not influence on cell viability. Wound-healing and MTT assays were performed on A375 melanoma cell line. Cells were transfected by siRNAs against LINC01420 (siLINC01420) or nonspecific siRNA (siControl). a. Representative images of wound-healing experiments are shown. b. The graph shows the dependence of wound width on time. Cells treated by siLINC01420 more quickly heal the wound than control cells. c. Result of MTT did not reveal the difference between cells treated by siLINC01420 and control cells. Error bars represent the mean ± SEM (standard error mean) of three independent experiments. *p < 0.01, vs. control (according to Mann–Whitney U test)