Fig. 5
From: Systems based analysis of human embryos and gene networks involved in cell lineage allocation
Chromatin modification enzymes/remodelling factors gene expression barcode data within individual 8-cell blastomeres. Frozen robust multi-array analysis (fRMA) was used to define absolute expression by comparison to publically available microarray datasets within R and an expression barcode was defined for each 8-cell blastomere. The heat map represents gene expression within individual 8-cell blastomeres expression barcode data, genes with a score of ‘1’ are present and ‘0’ are absent. The global epigenetic gene expression pattern reveals two groups of individual 8-cell blastomeres; B3/B4/B6 and B1/B2/B5/B7/B8