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Table 2 Top 15 up-regulated genes (L-lactate- vs. NaCl vehicle control)

From: L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells

Gene Symbol

Description

FC

ANOVA

FDR

TXNIP

thioredoxin interacting protein

21.97

1.14E-10

3.10E-07

H19

H19, imprinted maternally expressed transcript (non-protein coding)

12.36

8.95E-07

4.10E-05

AHSG

alpha-2-HS-glycoprotein

8.45

1.48E-08

4.00E-06

ARRDC4

arrestin domain containing 4

7.42

6.26E-10

6.94E-07

HAS2

hyaluronan synthase 2

7.31

4.80E-07

2.70E-05

PTX3

pentraxin 3, long

5.11

1.24E-07

1.20E-05

EREG

Epiregulin

5.05

3.57E-09

2.00E-06

NDUFA4L2

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2

4.65

3.63E-07

2.30E-05

LTC4S

leukotriene C4 synthase

4.54

3.33E-10

4.40E-07

LOC104976005

uncharacterized LOC104976005

4.47

2.47E-08

5.00E-06

RANBP3L

RAN binding protein 3-like

4.03

2.12E-08

4.00E-06

NPY

neuropeptide Y

4.03

1.90E-05

3.61E-04

CHRNA2; LOC101908817

cholinergic receptor, nicotinic, alpha 2 (neuronal); neuronal acetylcholine receptor subunit alpha-2-like

3.90

2.91E-10

4.18E-07

GFRA2

GDNF family receptor alpha 2

3.43

1.53E-11

1.45E-07

NDP

Norrie disease (pseudoglioma)

3.40

3.65E-08

6.00E-06