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Table 1 Summary of DNA methylation sites significantly rejecting the assumptions of linear regression

From: Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

 

Global

Skewness

Kurtosis

Link Function

Heteroskedasticity

N reject null hypothesis

577,919

332,457

544,460

59,572

35,001

% reject null hypothesis

71.8

41.3

67.6

7.4

4.3

  1. For each of the 5 tests performed by the gvlma package the number and percentage of DNA methylation sites with significant p-values (P < 9.42 × 10− 8) are reported