Fig. 2

Visualization of the hypergraph for the TCGA melanoma dataset with supervised grouping. a The plot of the entire network, where hyperedges were reduced to binary edges for visualization; b Detailed plot of the top 15 most connected vertices; c Sub-hypergraph centered at the module “DNA damage response, signal transduction by p53 class mediator”; d Sub-hypergraph centered at the module “DNA dependent DNA replication”. Vertex colors reflect the degree of connections, with more connected more red and less connected more yellow. Vertex sizes reflect the module sizes. The width of each edge is the rescaled edge weight. Three types of hypergraph edges are presented: type 1 edge connects only one vertex; type 2 edge connects two different vertices; and type 3 edge connects three different vertices