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Table 2 Distribution of differentially methylated CpGs among the ovarian methylomes

From: Dynamic DNA methylation of ovaries during pubertal transition in gilts

 

Detected CpGs

DMCs between Pre- and In-puberty

DMCs between Pre- and Post-puberty

DMCs between In- and Post-puberty

Number

Enrichment

Number

Enrichment

Number

Enrichment

Total

840,469

12,313

–

20,960

–

17,694

–

CGI

501,376

3813

0.30 (P < 2.22 × 10−16)

6324

0.29 (P < 2.22 × 10− 16)

5226

0.28 (P < 2.22 × 10− 16)

CGI shores

138,931

3161

1.74 (P < 2.22 × 10− 16)

5578

1.83 (P < 2.22 × 10− 16)

4778

1.87 (P < 2.22 × 10− 16)

CGI shelves

40,091

1141

2.04 (P < 2.22 × 10− 16)

2060

2.18 (P < 2.22 × 10− 16)

1672

2.08 (P < 2.22 × 10− 16)

Upstream

182,275

959

0.30 (P < 2.22 × 10− 16)

1678

0.31 (P < 2.22 × 10− 16)

1373

0.30 (P < 2.22 × 10− 16)

intron

219,465

4718

1.76 (P < 2.22 × 10− 16)

8051

1.76 (P < 2.22 × 10− 16)

6871

1.79 (P < 2.22 × 10− 16)

exon

214,079

1850

0.52 (P < 2.22 × 10− 16)

3376

0.56 (P < 2.22 × 10− 16)

2817

0.55 (P < 2.22 × 10− 16)

Downstream

46,202

759

1.12 (P < 2.22 × 10− 16)

1318

1.15 (P < 2.22 × 10− 16)

1138

1.18 (P < 2.22 × 10− 16)

Intergenic

178,448

4027

1.80 (P < 2.22 × 10− 16)

6537

1.68 (P < 2.22 × 10− 16)

5495

1.67 (P < 2.22 × 10− 16)

  1. Enrichment of DMCs for certain genomic regions was using a two-tailed Fisher’s exact test