Muscle cis-eQTL | Gene | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
SSC | N | SNP | Region (Mb) | P-value | q-value | B | δ ± SE | A1 | MAF | Acronym | Region (Mb) |
1 | 51 | ASGA0000817 | 0.2–9.9 | 6.69E-08 | 2.12E-04 | 1.91E-03 | −0.37 ± 0.06 | A | 0.388 | ARID1B | 9.7–10.2 |
1 | 15 | ALGA0002427 | 32.2–36.6 | 2.74E-11 | 5.90E-07 | 7.80E-07 | 0.58 ± 0.06 | A | 0.365 | AKAP7 | 32.2–32.3 |
1 | 10 | INRA0003613 | 101.9–108.9 | 3.29E-12 | 2.00E-08 | 9.00E-08 | −0.29 ± 0.03 | C | 0.433 | WDR7 | 106.0–106.4 |
1 | 2 | MARC0039560 | 125.9–128.7 | 5.67E-06 | 3.24E-02 | 1.62E-01 | −0.16 ± 0.03 | G | 0.481 | HYPK | 127.7–127.7 |
1 | 5 | DIAS0000210 | 183.3–183.9 | 5.36E-07 | 7.63E-03 | 1.53E-02 | 0.28 ± 0.05 | C | 0.466 | CNIH1 | 183.8–183.8 |
1 | 9 | ASGA0006202 | 231.0–239.7 | 3.49E-11 | 8.10E-07 | 9.90E-07 | 0.50 ± 0.07 | A | 0.115 | GRHPR | 238.1–238.1 |
1 | 18 | M1GA0001375 | 240.2–249.6 | 1.92E-13 | 1.00E-08 | 1.00E-08 | 0.27 ± 0.03 | A | 0.399 | ALG2 | 240.9–240.9 |
1 | 1 | H3GA0004649 | 260.9–260.9 | 2.36E-06 | 3.24E-02 | 6.73E-02 | −0.36 ± 0.07 | A | 0.17 | PSMD5 | 260.8–260.8 |
2 | 1 | ALGA0011482 | 5.8–5.8 | 1.47E-06 | 4.20E-02 | 4.20E-02 | 0.28 ± 0.06 | A | 0.144 | CTSF | 5.8–5.8 |
2 | 22 | MARC0095742 | 32.5–39.3 | 4.52E-10 | 4.30E-06 | 1.29E-05 | −0.53 ± 0.08 | A | 0.354 | HTATIP2 | 39.0–39.0 |
2 | 24 | ALGA0013197 | 33.0–39.3 | 1.24E-14 | 0.00E+ 00 | 0.00E+ 00 | −0.52 ± 0.06 | A | 0.25 | PRMT3 | 38.8–39.0 |
2 | 4 | ALGA0115180 | 115.1–116.1 | 9.98E-09 | 2.36E-04 | 2.84E-04 | 0.37 ± 0.06 | A | 0.141 | WDR36 | 115.8–115.9 |
2 | 8 | DIAS0000550 | 140.2–145.0 | 1.54E-06 | 1.97E-02 | 4.40E-02 | −0.31 ± 0.05 | G | 0.466 | ETF1 | 140.4–140.5 |
2 | 15 | H3GA0055810 | 147.1–148.7 | 2.30E-08 | 6.56E-04 | 6.56E-04 | −0.30 ± 0.05 | G | 0.16 | LARS | 147.4–147.5 |
3 | 1 | MARC0045458 | 3.6–3.6 | 3.41E-08 | 9.72E-04 | 9.72E-04 | 0.26 ± 0.04 | G | 0.223 | AP5Z1 | 3.6–3.6 |
3 | 2 | MARC0020406 | 4.1–4.2 | 4.17E-08 | 7.28E-04 | 1.19E-03 | −0.68 ± 0.12 | A | 0.121 | ZNF12 | 4.4–4.4 |
3 | 14 | ALGA0017913 | 18.6–19.8 | 1.33E-09 | 1.78E-05 | 3.78E-05 | 0.30 ± 0.05 | G | 0.125 | NSMCE1 | 19.6–19.6 |
3 | 2 | DRGA0003838 | 29.6–29.6 | 5.05E-07 | 7.81E-03 | 1.44E-02 | −0.37 ± 0.06 | A | 0.37 | MKL2 | 28.9–29.2 |
3 | 26 | MARC0101576 | 30.0–34.4 | 5.74E-09 | 1.64E-04 | 1.64E-04 | −0.22 ± 0.04 | G | 0.345 | RSL1D1 | 31.2–31.2 |
3 | 17 | MARC0000159 | 48.6–54.6 | 2.77E-06 | 9.87E-03 | 7.89E-02 | −0.27 ± 0.06 | G | 0.194 | MRPS9 | 49.6–49.6 |
3 | 18 | MARC0049447 | 93.7–97.2 | 3.90E-07 | 2.78E-03 | 1.11E-02 | 0.29 ± 0.05 | A | 0.272 | THADA | 96.8–97.1 |
3 | 7 | M1GA0026608 | 126.9–127.8 | 4.55E-09 | 6.48E-05 | 1.30E-04 | 0.58 ± 0.10 | A | 0.178 | CYS1 | 126.3–126.4 |
4 | 6 | ASGA0018519 | 14.3–15.8 | 3.76E-06 | 3.03E-02 | 1.07E-01 | −0.21 ± 0.04 | C | 0.393 | NDUFB9 | 15.1–15.1 |
4 | 2 | ASGA0018539 | 14.6–14.6 | 9.98E-09 | 2.84E-04 | 2.84E-04 | 0.19 ± 0.03 | G | 0.322 | WASHC5 | 14.5–14.6 |
4 | 6 | ALGA0024302 | 30.2–31.5 | 2.51E-06 | 9.62E-03 | 7.15E-02 | −0.40 ± 0.07 | G | 0.433 | OXR1 | 30.7–31.2 |
4 | 11 | DIAS0000176 | 95.2–99.8 | 2.07E-07 | 1.97E-03 | 5.91E-03 | 0.33 ± 0.06 | A | 0.252 | APH1A | 98.8–98.8 |
4 | 4 | M1GA0006152 | 95.3–96.1 | 3.55E-07 | 1.01E-02 | 1.01E-02 | −0.23 ± 0.04 | G | 0.341 | S100A13 | 96.0–96.0 |
5 | 4 | ASGA0104541 | 20.3–23.5 | 1.61E-06 | 1.57E-02 | 4.59E-02 | 0.17 ± 0.03 | A | 0.325 | TSPAN31 | 23.0–23.0 |
5 | 12 | SIRI0000318 | 25.6–29.4 | 2.96E-07 | 2.11E-03 | 8.43E-03 | −0.53 ± 0.10 | A | 0.306 | TMEM5 | 28.2–28.2 |
5 | 24 | MARC0113779 | 80.3–84.7 | 2.66E-10 | 7.10E-07 | 7.58E-06 | −0.39 ± 0.06 | A | 0.136 | C12orf73 | 80.5–80.5 |
6 | 25 | ASGA0098408 | 17.0–21.7 | 1.11E-08 | 1.40E-04 | 3.16E-04 | 0.49 ± 0.08 | G | 0.24 | ARL2BP | 19.2–19.2 |
6 | 28 | DIAS0004785 | 45.5–55.4 | 4.23E-06 | 1.72E-02 | 1.21E-01 | −0.15 ± 0.03 | A | 0.471 | RABAC1 | 49.9–49.9 |
6 | 13 | ASGA0094600 | 70.1–71.6 | 8.61E-07 | 7.64E-03 | 2.45E-02 | −0.33 ± 0.06 | G | 0.296 | LZIC | 70.2–70.2 |
6 | 17 | MARC0031169 | 70.1–71.6 | 3.65E-06 | 1.16E-02 | 1.04E-01 | −0.19 ± 0.03 | G | 0.279 | DFFA | 70.7–70.7 |
6 | 36 | ASGA0028827 | 81.9–89.9 | 5.30E-12 | 1.00E-08 | 1.50E-07 | −0.39 ± 0.05 | G | 0.238 | BSDC1 | 88.8–88.8 |
6 | 52 | MARC0015713 | 90.6–99.9 | 2.96E-08 | 4.21E-04 | 8.43E-04 | −0.20 ± 0.03 | A | 0.379 | AFG3L2 | 97.2–97.2 |
6 | 2 | ALGA0122704 | 95.9–99.4 | 3.18E-06 | 6.66E-03 | 9.05E-02 | 0.37 ± 0.08 | A | 0.327 | RAB12 | 99.2–99.2 |
6 | 6 | ALGA0037549 | 157.5–158.8 | 2.07E-08 | 5.89E-04 | 5.89E-04 | 0.29 ± 0.05 | A | 0.262 | MRPL37 | 158.0–158.1 |
6 | 1 | ASGA0030033 | 158.6–158.6 | 5.27E-06 | 2.15E-02 | 1.50E-01 | −0.22 ± 0.05 | G | 0.359 | YIPF1 | 158.4–158.4 |
7 | 19 | ASGA0035147 | 86.3–89.1 | 1.55E-12 | 4.00E-08 | 4.00E-08 | 0.41 ± 0.05 | A | 0.5 | MTHFD1 | 88.4–88.5 |
7 | 21 | ALGA0043682 | 92.1–99.8 | 7.12E-09 | 2.03E-04 | 2.03E-04 | −0.26 ± 0.04 | G | 0.333 | DCAF5 | 92.7–92.8 |
8 | 11 | ALGA0112294 | 10.6–17.6 | 1.63E-09 | 6.63E-06 | 4.64E-05 | −0.25 ± 0.04 | C | 0.399 | TAPT1 | 11.3–11.4 |
8 | 6 | ALGA0049334 | 117.4–118.2 | 9.95E-09 | 8.85E-05 | 2.84E-04 | −0.29 ± 0.05 | A | 0.335 | BDH2 | 117.9–117.9 |
9 | 37 | ASGA0042057 | 20.2–24.2 | 2.61E-10 | 7.44E-06 | 7.44E-06 | 0.56 ± 0.08 | G | 0.49 | CTSC | 21.7–21.7 |
9 | 9 | ASGA0043022 | 40.3–47.6 | 8.95E-11 | 2.55E-06 | 2.55E-06 | −0.28 ± 0.03 | A | 0.165 | ARHGEF12 | 47.4–47.6 |
10 | 4 | ASGA0046443 | 10.0–14.1 | 1.10E-16 | 0.00E+ 00 | 0.00E+ 00 | −0.92 ± 0.09 | G | 0.228 | MARC2 | 10.1–10.1 |
10 | 11 | ASGA0048312 | 51.7–58.7 | 5.83E-08 | 1.66E-03 | 1.66E-03 | −0.33 ± 0.04 | A | 0.409 | COMMD3 | 52.5–52.6 |
10 | 2 | ALGA0059373 | 54.1–54.4 | 4.39E-08 | 6.26E-04 | 1.25E-03 | 0.33 ± 0.06 | G | 0.298 | PLXDC2 | 54.2–54.6 |
11 | 3 | DIAS0002284 | 20.7–21.0 | 3.50E-08 | 9.98E-04 | 9.98E-04 | −0.21 ± 0.04 | A | 0.296 | ESD | 20.6–20.6 |
12 | 4 | ALGA0115312 | 4.2–4.8 | 4.24E-07 | 1.21E-02 | 1.21E-02 | −0.20 ± 0.04 | G | 0.296 | ST6GALNAC2 | 4.9–4.9 |
12 | 3 | DRGA0011563 | 4.2–4.8 | 3.95E-06 | 3.75E-02 | 1.13E-01 | −0.42 ± 0.07 | A | 0.17 | EXOC7 | 5.3–5.3 |
12 | 3 | ALGA0064915 | 10.9–11.6 | 1.19E-06 | 1.70E-02 | 3.39E-02 | −0.40 ± 0.08 | G | 0.291 | ABCA5 | 11.0–11.1 |
12 | 16 | MARC0016809 | 20.3–24.8 | 3.26E-12 | 9.00E-08 | 9.00E-08 | 0.49 ± 0.06 | G | 0.272 | PNPO | 24.1–24.2 |
12 | 2 | DIAS0000973 | 23.5–23.6 | 1.52E-06 | 2.34E-02 | 4.33E-02 | 0.24 ± 0.04 | C | 0.257 | MRPL10 | 24.0–24.0 |
12 | 8 | DIAS0000242 | 40.0–48.8 | 3.14E-06 | 2.01E-02 | 8.96E-02 | 0.25 ± 0.05 | G | 0.433 | TMEM98 | 42.0–42.1 |
12 | 6 | ASGA0054801 | 44.3–46.5 | 1.28E-06 | 2.18E-02 | 3.66E-02 | 0.20 ± 0.04 | G | 0.481 | TMEM97 | 44.6–44.6 |
12 | 7 | ALGA0066917 | 50.5–59.3 | 4.57E-11 | 4.50E-07 | 1.30E-06 | 0.37 ± 0.05 | G | 0.335 | RABEP1 | 51.6–51.8 |
12 | 1 | ALGA0120796 | 51.9–51.9 | 2.27E-07 | 6.46E-03 | 6.46E-03 | −0.13 ± 0.02 | C | 0.412 | PSMB6 | 52.0–52.0 |
12 | 7 | MARC0002558 | 59.0–59.9 | 3.63E-10 | 1.03E-05 | 1.03E-05 | 0.41 ± 0.05 | A | 0.35 | ALDH3A2 | 59.9–59.9 |
13 | 2 | ALGA0067450 | 2.5–2.7 | 7.69E-07 | 2.19E-02 | 2.19E-02 | 0.34 ± 0.06 | A | 0.306 | SH3BP5 | 2.5–2.5 |
13 | 9 | ASGA0086643 | 12.4–14.4 | 1.64E-12 | 1.00E-08 | 5.00E-08 | 0.52 ± 0.06 | A | 0.422 | NGLY1 | 12.6–12.6 |
13 | 5 | ALGA0068741 | 19.4–23.1 | 1.67E-06 | 2.38E-02 | 4.77E-02 | −0.16 ± 0.03 | G | 0.269 | PDCD6IP | 19.5–19.6 |
13 | 5 | MARC0000523 | 31.1–32.5 | 3.32E-11 | 9.50E-07 | 9.50E-07 | −0.35 ± 0.05 | A | 0.155 | MAPKAPK3 | 33.0–33.1 |
14 | 12 | H3GA0038597 | 6.1–7.2 | 6.65E-13 | 2.00E-08 | 2.00E-08 | −0.23 ± 0.03 | A | 0.383 | POLR3D | 6.5–6.5 |
14 | 1 | SIRI0001291 | 22.7–22.7 | 4.88E-08 | 1.39E-03 | 1.39E-03 | −0.20 ± 0.03 | G | 0.291 | PGAM5 | 22.7–22.7 |
14 | 8 | MARC0094155 | 40.6–43.2 | 4.74E-10 | 5.71E-06 | 1.35E-05 | −0.44 ± 0.06 | G | 0.212 | ACADS | 40.6–40.6 |
14 | 5 | ASGA0065742 | 102.7–106.9 | 3.84E-08 | 5.48E-04 | 1.10E-03 | −0.34 ± 0.06 | A | 0.147 | IDE | 103.9–104.1 |
14 | 4 | MARC0043866 | 110.5–111.0 | 2.01E-06 | 2.86E-02 | 5.72E-02 | 0.30 ± 0.05 | A | 0.49 | COX15 | 110.8–110.8 |
14 | 11 | ALGA0081813 | 124.1–125.1 | 1.19E-08 | 1.70E-04 | 3.39E-04 | 0.44 ± 0.07 | G | 0.277 | CASP7 | 124.0–124.0 |
15 | 11 | ASGA0069526 | 42.2–49.0 | 7.12E-13 | 0.00E+ 00 | 2.00E-08 | 1.33 ± 0.16 | G | 0.067 | SORBS2 | 46.5–46.9 |
15 | 54 | ALGA0085678 | 54.5–69.7 | 4.49E-08 | 1.28E-03 | 1.28E-03 | −0.36 ± 0.06 | G | 0.112 | UGGT1 | 59.1–59.2 |
15 | 9 | ASGA0070490 | 116.4–118.5 | 1.07E-10 | 3.05E-06 | 3.05E-06 | 0.35 ± 0.05 | A | 0.471 | XRCC5 | 118.3–118.4 |
16 | 1 | ALGA0090252 | 34.2–34.2 | 1.21E-06 | 3.45E-02 | 3.45E-02 | −0.24 ± 0.04 | C | 0.485 | SLC38A9 | 34.7–34.8 |
16 | 6 | MARC0049616 | 72.0–73.1 | 7.13E-08 | 1.46E-03 | 2.03E-03 | −0.32 ± 0.05 | A | 0.288 | CCT5 | 72.2–72.2 |
17 | 2 | ALGA0096195 | 57.0–57.1 | 9.93E-08 | 1.42E-03 | 2.83E-03 | −0.36 ± 0.05 | A | 0.223 | FAM210B | 56.9–56.9 |
18 | 5 | ALGA0097540 | 24.4–25.8 | 1.38E-07 | 3.94E-03 | 3.94E-03 | 0.44 ± 0.08 | A | 0.142 | FAM3C | 25.5–25.6 |