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Table 3 Biological processes potentially regulated by the 17 DEMs. The 17 miRNAs were selected as having more than a mean of 20 reads. Process Networks analysis using Metacore™ software. * indicate processes linked with cytoskeleton and cell life and § indicate signal transduction processes. FDR: False Discovery Rate

From: Deep RNA-Seq reveals miRNome differences in mammary tissue of lactating Holstein and Montbéliarde cows

 

#

Networks

FDR

§

1

Signal transduction NOTCH signaling

8.56E-07

*

2

Cytoskeleton regulation of cytoskeleton rearrangement

2.17E-05

*

3

Development blood vessel morphogenesis

2.57E-05

§

4

Signal transduction WNT signaling

2.92E-04

*

5

Development regulation of angiogenesis

2.92E-04

 

6

Development neurogenesis axonal guidance

2.92E-04

 

7

Immune response TCR signaling

2.93E-04

*

8

Cell cycle G1-S growth factor regulation

3.48E-04

*

9

Apoptosis anti-apoptosis mediated by external signals via NF-kB

3.48E-04

*

10

Cytoskeleton actin filament

6.87E-04

*

11

Proliferation lymphocyte proliferation

9.41E-04

 

12

Inflammation Protein C signaling

1.05E-03

*

13

Development EMT regulation of epithelial-to-mesenchymal transition

1.09E-03

*

14

Cell adhesion attractive and repulsive receptors

1.33E-03

 

15

Cardiac development FGF ErbB signaling

1.36E-03

*

16

Proliferation positive regulation cell proliferation

1.36E-03

*

17

Cell cycle G2-M

1.36E-03

 

18

Development Hedgehog signaling

1.60E-03

*

19

Cell cycle G1-S interleukin regulation

1.68E-03

 

20

Reproduction FSH-beta signaling pathway

1.68E-03