Fig. 4

Weighted gene coexpression network (WGCNA) analysis of genes in all samples. a Hierarchical cluster tree representing the coexpression modules identified by WGCNA. Each leaf in the tree represents one gene. The major tree branches constitute 14 modules [fragments per kilo base of exon per million reads mapped (FPKM) ≥1, module similarity threshold ≥0.25], labeled with different colors. b Module–sample association. Each row corresponds to a module and it is labeled with a different color as in (a). Each column corresponds to a sample. The color of each cell at the row–column intersection indicates the correlation coefficient between the module and the sample. Each cell represents the correlation value between the module and each sample; the upper number is the correlation value, and the number underneath that is the p-value (significant at p < 0.05)