The effect of age on DNA methylation in whole blood among Bangladeshi men and women

BMC Genomics

Table 1 Characteristics of study participants, by sex

	Males (N = 189)		Females (N = 211)
	N	%	N	%	P value*
Age					0.0099*
<35	36	19.0	50	23.7
≥35-<45	61	32.3	53	25.1
≥45-<55	67	35.4	57	27.0
≥55	25	13.2	51	24.2
BMI					0.2527*
<18.5	65	34.4	87	41.2
≥18.5-<24.5	99	52.4	106	50.2
≥24.5	25	13.2	18	8.5
Smoking					< 0.0001*
Never	7	3.7	102	48.3
Ever	182	96.3	109	51.7
Urinary Total Arsenic Concentration (μg/g)					0.0004*
<15	62	32.8	36	17.1
≥15 - < 37.5	48	25.4	54	25.6
≥37.5 - < 104.2	46	24.3	54	25.6
≥104.2	33	17.5	67	31.8
	mean	range	mean	range	P value*
Average Blood Cell Percentages (estimated by MethylSpectrum)
CD8T	0.22	0.07–0.38	0.2	0.05–0.42	0.0437*
CD4T	0.07	0–0.25	0.05	0–0.23	0.0016*
NK	0.02	0–0.09	0.03	0–0.09	< 0.0001*
Bcell	0.08	0.03–0.20	0.08	0.02–0.15	0.8230*
Mono	0.07	0–0.14	0.08	0–0.15	0.0046*
Gran	0.48	0.34–0.63	0.49	0.31–0.70	0.0909*

Abreviations: N Number, % Percent
*Chi-squared test used for categorical variable and t-test used for continuous variables

ISSN: 1471-2164