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Table 2 Comparison of local network alignment quality of three previous algorithms and the proposed method in terms of the average inter-species semantic similarity (ISS), the average number of conserved edges (CE), and the average number of functionally consistent conserved edges (F-CE)

From: LePrimAlign: local entropy-based alignment of PPI networks to predict conserved modules

 

Human-yeast network alignment

Human-fruit fly network alignment

Yeast-fruit fly network alignment

Algorithms

ISS

CE

F-CE

ISS

CE

F-CE

ISS

CE

F-CE

NetworkBlast

0.364

30.461

26.659

0.177

16.301

10.470

0.242

5.845

5.634

AlignMCL

0.292

2.984

2.459

0.144

0.713

0.492

0.185

0.280

0.241

LocalAli

0.117

2.375

1.845

0.066

0.980

0.625

0.104

0.740

0.526

LePrimAlign

0.373

17.944

15.872

0.198

22.787

17.470

0.235

13.884

13.661