Table 1 Domain combination in nAChR genes from different species
From: Massive expansion and diversity of nicotinic acetylcholine receptors in lophotrochozoans
Domain combinations | P. f. martensii | C. gigas | M. yessoensis | B. platifrons | M. philippinarum | L. gigantea | A. californica | O. bimaculoides | C. teleta | H. robusta | A. digitifera | E. pallida | D. rerio | H. sapiens |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LBD-NTM | 156 | 90 | 107 | 56 | 126 | 57 | 89 | 41 | 70 | 33 | 30 | 52 | 28 | 16 |
LBD-NTM-TM | 16 | 5 | 7 | 3 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
LBD | 8 | 10 | 7 | 8 | 17 | 4 | 19 | 18 | 34 | 6 | 5 | 6 | 0 | 0 |
LBD-TM | 8 | 2 | 3 | 5 | 11 | 2 | 3 | 7 | 9 | 5 | 0 | 0 | 0 | 0 |
NTM | 3 | 0 | 0 | 6 | 5 | 0 | 4 | 6 | 1 | 2 | 1 | 0 | 0 | 0 |
NTM-TM | 4 | 4 | 1 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 2 | 3 | 0 | 0 |
TM-LBD-NTM | 1 | 1 | 4 | 0 | 1 | 0 | 1 | 0 | 1 | 2 | 0 | 1 | 0 | 0 |
TM-LBD-NTM-TM | 4 | 1 | 4 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TM-LBD | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-LBD-NTM-LBD-NTM | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TM-NTM | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
LBD-LBD-NTM | 1 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 |
LBD-NTM-LBD | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-LBD-NTM-TM | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-LBD-MTM-TM | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-TM-LBD-NTM | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-LBD-NTM-LBD-NTM-TM | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-LBD-NTM | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
LBD-NTM-NTM | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-TM-LBD-NTM-TM | 0 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-TM-LBD-TM | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TM-LBD-TM | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 |
LBD-LBD-TM | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-LBD | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-NTM-TM | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NTM-TM-LBD-NTM-TM | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-TM-LBD-NTM-TM | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-TM-NTM | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
TM-NTM-TM | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-TM-LBD-NTM | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-NTM-LBD-NTM-TM | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TM-LBD-TM-LBD-NTM-TM | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LBD-LBD-TM-LBD-NTM | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
LBD-LBD-NTM-NTM | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
with other functional domains | 9 | 8 | 3 | 6 | 5 | 1 | 2 | 2 | 0 | 2 | 2 | 1 | 0 | 0 |
| Â | 217 | 132 | 138 | 99 | 182 | 64 | 127 | 78 | 129 | 52 | 42 | 66 | 28 | 17 |