Transcriptome analysis reveals mechanism underlying the differential intestinal functionality of laying hens in the late phase and peak phase of production

Table 6 The differentially expressed genes¹ (|fold change| > 1.3 at a false discovery rate < 0.05) that mapped to the enriched pathways (n = 4)

KEGG pathways	Pathway_ID	Differentially expressed genes (Fold change)
PPAR signaling pathway	ko03320	FABP1 (0.38), FABP2 (0.49), FABP3 (0.41), FABP5 (0.69), FABP6 (0.58), LPL (0.56), APOA1 (0.56), SCP2 (0.75), PLIN1 (0.59)
Oxidative phosphorylation	ko00190	NDUFS6 (0.76), NDUFA1 (0.66), NDUFA8 (0.74), NDUFB2 (0.69), NDUFB9 (0.76), UQCR9 (0.65), ATP5H (0.72), ATP5I (0.68), ATP5J (0.69), ATP5L (0.66), ATP6V1G1 (0.76)
Glutathione metabolism	ko00480	GSTA3 (0.69), GSTM2 (0.59), GSTO1 (0.73), ODC1 (0.68)
Drug metabolism-cytochrome P450	ko00982	GSTA3 (0.69), GSTM2 (0.59), GSTO1 (0.73)
Metabolism of xenobiotics by cytochrome P450	ko00980	GSTA3 (0.69), GSTM2 (0.59), GSTO1 (0.73)
Glycine, serine and threonine metabolism	ko00260	LOC418544 (0.55), GLDC (0.51), LOC107051323 (0.51)

¹FABP fatty acid-binding protein, LPL lipoprotein lipase, APOA apolipoprotein A, SCP sterol carrier protein, PLIN perilipin, NDUFS NADH dehydrogenase (ubiquinone) Fe-S protein, NDUFA NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit, NDUFB NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit, UQCR ubiquinol-cytochrome c reductase subunit, ATP5H ATP synthase subunit d, ATP5I ATP synthase subunit e, ATP5J ATP synthase subunit f, ATP5L ATP synthase subunit g, ATP6V1G V-type proton ATPase subunit G, GSTA3 glutathione S-transferase alpha 3, GSTM2 glutathione S-transferase mu 2, GSTO1 glutathione S-transferase omega-1, ODC1 ornithine decarboxylase 1, LOC418544 cystathionine beta-synthase-like isoform, GLDC glycine dehydrogenase, LOC107051323 glycine hydroxymethyltransferase

ISSN: 1471-2164