Fig. 6

JAK-STAT pathway plays a key role in bacterial clearance. a & b Bacterial count (Colony forming units, CFU) in V.alginolyticus (a) and V.parahemolyticus (b) infected surf clams treated with JAK/STAT pathway inhibitors Ruxolitinib and Methotrexate. DMSO treatment was used as controls. N = 3. c Apoptosis index (%) in V.alginolyticus and V.parahemolyticus infected surf clams treated with JAK/STAT pathway inhibitors Ruxolitinib and Methotrexate. DMSO treatment was used as controls. The infected clams were compared with uninfected controls. N = 5