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Table 3 Functional enrichment of non-redundant differentially expressed genes presenting higher variation in the skin of tick-susceptible Braford cattle after tick infestation

From: Network analysis uncovers putative genes affecting resistance to tick infestation in Braford cattle skin

Category

Function Annotation

p-value

z-scorea

Genesb

Cell Signaling, Molecular Transport, Vitamin and Mineral Metabolism

quantity of Ca2+

1.74E-03

2.17

CCL3, CXCL11, GCGR, TAC1, TNFRSF9, TNFSF11

Cell-To-Cell Signaling and Interaction, Hematological System Development and Function, Immune Cell Trafficking

adhesion of immune cells

6.86E-04

2.15

CCL3, CXCL11, FCAR, TAC1, TNFRSF9, TNFSF11

Cell-To-Cell Signaling and Interaction, Inflammatory Response

immune response of leukocytes

2.44E-03

2.20

CCL3, FCAR, TNFRSF9, TNFSF11, TREM2

Cellular Movement, Hematological System Development and Function, Immune Cell Trafficking

cell movement of leukocytes

9.12E-04

2.41

CCL3, CXCL11, DMBT1, FCAR, TAC1, TG, TNFRSF9, TNFSF11, TREM2

cell movement of antigen presenting cells

9.33E-05

2.17

CCL3, CXCL11, DMBT1, FCAR, TAC1, TNFRSF9, TREM2

Cellular Movement, Hematological System Development and Function, Immune Cell Trafficking, Inflammatory Response

cell movement of phagocytes

3.56E-04

2.25

CCL3, CXCL11, DMBT1, FCAR, TAC1, TNFRSF9, TNFSF11, TREM2

cell movement of macrophages

1.14E-03

2.22

CCL3, DMBT1, FCAR, TNFRSF9, TREM2

  1. aactivation z-score (|z-score| > 2)
  2. bnon-redundant TopDEGs (|log2| FC > 1)
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BMC Genomics

ISSN: 1471-2164

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