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Table 1 SNPs and indels identified in P. aeruginosa PAO1161 genome, resulting in expression of truncated proteins. The effect of a mutation is predicted using the PAO1-UW genome as a reference. In case of PA2492 (mexT) the nucleotide changes are proposed to alter the start codon and hence the sequence of N-terminal part

From: Genome sequence of Pseudomonas aeruginosa PAO1161, a PAO1 derivative with the ICEPae1161 integrative and conjugative element

Mutation effect

PAO1-UW position

Nucleotide change

AA change

length PAO1/PAO1161

PAO1 gene

PAO1161 ID

Description

stop codon

2,121,203

C → T

W340*

665 /339

PA1939

D3C65_15950

putative ATP-dependent endonuclease of the OLD family

2,356,682

CC → C

L173*

182 /172

PA2141

D3C65_14865

CinA family protein

3,097,884

G → A

Q209*

792 / 208

PA2735

D3C65_11725

SAM-dependent DNA methyltransferase

frame-shift

740,419

G → GC

V73

381 / 124

PA0683 (hxcY)

D3C65_22610

putative type II secretion system protein

1,440,623

AA → A

K640

656 /642

PA1327

D3C65_19175

putative protease

1,835,045

G → GCa

S218

249 / 226

PA1685 (masA)

D3C65_17305

enolase-phosphatase E-1

2,807,706

CAGCCGGCC → C

aa1–78/ 35aa

347 / 304

PA2492 (mexT)

D3C65_13040

transcriptional regulator

  1. a−SNP at this position in PAO1DSM / MPAO-1 [7] but a nucleotide insertion in our study