Table 3 Co-expressed gene pairs and their common associated diseases/traits
From: Detecting fitness epistasis in recently admixed populations with genome-wide data
Chr | Gene in region 1 | Gene in region 2 | Disease/trait | Significant tissues |
|---|---|---|---|---|
Chr 1 | AK5 | CADM3 | Educational attainment (years of education) | Brain Nucleus accumbens basal ganglia |
Chr 1 | DPH5 | DAP3 | Inflammatory bowel disease | Uterus |
Chr 1 | ELTD1 | DARC | White blood cell count | Artery Aorta;Artery Tibial; Colon Transverse; Esophagus Gastroesophageal Junction; Esophagus Mucosa; Ovary; Skin Not Sun Exposed Suprapubic; Vagina |
Chr 1 | ELTD1 | DCST2 | Eosinophil counts | Adipose Subcutaneous |
Chr 1 | GFI1 | SLAMF7 | Multiple sclerosis | Heart Atrial Appendage; Ovary; Uterus |
Chr 1 | MIR137HG | CADM3 | Educational attainment (years of education) | Brain Hypothalamus |
Chr 1 | MTF2 | NDUFS2 | Eosinophil counts | Brain Hippocampus |
Chr 1 | PKN2 | ASH1L | Red blood cell count | Skin Not Sun Exposed Suprapubic |
Chr 10 | CAMK1D | JMJD1C | General cognitive ability | Brain Hypothalamus |
Chr 10 | CAMK1D | JMJD1C | Educational attainment | Brain Hypothalamus |
Chr 10 | CAMK1D | JMJD1C | Educational attainment (years of education) | Brain Hypothalamus |
Chr 10 | CAMK1D | JMJD1C | Highest math class taken | Brain Hypothalamus |
Chr 10 | CAMK1D | JMJD1C | Lung function (FEV1/FVC) | Brain Hypothalamus |
Chr 10 | CAMK1D | JMJD1C | Educational attainment | Brain Hypothalamus |
Chr 10 | CELF2 | CCDC6 | Systolic blood pressure | Spleen |
Chr 10 | CELF2 | CCDC6 | Pulse pressure | Spleen |
Chr 10 | FAM107B | CTNNA3 | Night sleep phenotypes | Brain Caudate basal ganglia; Brain Cortex; Brain Nucleus accumbens basal ganglia; Brain Putamen basal ganglia |
Chr 10 | FRMD4A | REEP3 | Red blood cell count | Breast Mammary Tissue |
Chr 10 | NEBL | JMJD1C | Interleukin-10 levels | Pituitary |
Chr 10 | NEBL | JMJD1C | Lung function (FEV1/FVC) | Pituitary |
Chr 10 | PIP4K2A | CTNNA3 | Breast cancer | Brain Caudate basal ganglia; Brain Cortex; Brain Nucleus accumbens basal ganglia |
Chr 10 | PIP4K2A | CTNNA3 | Obesity-related traits | Brain Caudate basal ganglia; Brain Cortex; Brain Nucleus accumbens basal ganglia |
Chr 10 | PLXDC2 | BICC1 | Heel bone mineral density | Stomach |
Chr 10 | PLXDC2 | BICC1 | Pulse pressure | Stomach |