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Table 2 SK-MEL-2 telomere lengths

From: Single-molecule analysis of subtelomeres and telomeres in Alternative Lengthening of Telomeres (ALT) cells

 

End telomere

End telomere loss

Recombined Ends with ITS

ITS Loss

(TTAGGG) n < 500 bp

% Recombinant Subtelomere Molecules

% of total analyzed for subtelomere

Longest Telomere

Chr-parm

Mean Length (kb) ± Std (# telomeres)

(# molecules)

Mean Length (kb) ± Std (# telomeres)

(# molecules)

# molecules (# end, # ITS)

Length (kb)

1p

4.5 ± 3.4 (24)

0

nd

0

1 (1,0)

0

12.2

2p

3.1 ± 4.1 (33)

2

nd

0

5 (5,0)

0

18.8

3p

4.2. ± 3.6 (28)

0

nd

0

5 (4,0)

0

14.6

4p

2.9 ± 3.2 (4)

0

nd

0

0 (0,0)

0

7.7

5p

N/A

N/A

N/A

N/A

N/A

N/A

N/A

6p

2.1 ± 2.1 (13)

0

nd

0

1 (1,0)

0

7.5

7p

1.8 ± 2.0 (14)

2

nd

0

3 (3,0)

0

5.7

8p

2.9 ± 2.8 (31)

5

10.3 ± 0 (1)

0

5 (5,0)

3

11.7

9p

3.1 ± 3.2 (34)

1

2.6 ± 2.5 (5)

0

4 (4,0)

13

14.1

10p

3.2 ± 3.2 (26)

2

2.9 ± 0 (1)

0

2 (2,0)

4

11.2

11p

N/A

N/A

N/A

N/A

N/A

N/A

N/A

12p

2.6 ± 2.0 (27)

2

4.0 ± 4.5 (2)

0

2 (2,0)

7

6.6

13p

nr

 

nr

    

14p

nr

 

nr

    

15p

nr

 

nr

    

16p

INP

 

INP

    

17p

INP

 

INP

    

18p

2.2 ± 2.6 (9)

1

1.1 ± 0 (1)

0

1 (1,0)

10

8.7

19p

2.7 ± 3.0 (32)

1

5.1 ± 3.9 (5)

0

4 (4,0)

14

13.2

20p

4.8 ± 5.2 (16)

1

4.6 ± 2.5 (4)

0

2 (2,0)

20

16.4

21p

nr

 

nr

    

22p

nr

 

nr

    

Xp/Yp

nr

 

nr

    

Chr-qarm

 1q

4.3 ± 3.6 (25)

1

3.9 ± 2.0 (5)

0

2 (2,0)

17

12

 2q

2.5 ± 2.4 (30)

1

3.6 ± 1.1 (3)

0

3 (3,0)

9

8.6

 3q

nd

0

4.1 ± 9.2 (7)

4

1 (0,1)

100

24.9

 4q

N/A

N/A

N/A

N/A

N/A

N/A

N/A

 5q

4.1 ± 3.3 (34)

0

2.4 ± 0 (1)

0

2 (2,0)

3

14.4

 6q

3.3 ± 3.6 (24)

6

nd

nd

0 (0,0)

0

13.8

 7q

4.0 ± 8.0 (22)

2

4.7 ± 2.3 (6)

0

8 (7,1)

21

47.3

 8q

4.0 ± 4.0 (28)

1

2.1 ± 0 (1)

nd

1 (1,0)

0

12.9

 9q

1.3 ± 2.0 (7)

4

nd

0

0 (0,0)

0

4.4

 10q

3.6 ± 4.1 (20)

1

7.8 ± 6.8 (2)

0

2 (2,0)

9

13.6

 11q

3.0 ± 4.7 (10)

4

nd

0

1 (1,0)

0

13.6

 12q

4.9 ± 4.3 (31)

2

nd

0

3 (3,0)

0

13.7

 13q

3.4 ± 2.8 (27)

3

nd

0

1 (1,0)

0

9.3

 14q

1.7 ± 3.0 (23)

4

nd

0

8 (8,0)

0

14.3

 15q

4.8 ± 3.5 (30)

1

nd

0

nd

0

14.3

 16q

1.3 ± 1.1 (20)

2

4.4 ± 4.6 (4)

0

4 (4,0)

17

3.5

 17q

3.1 ± 4.3 (30)

2

4.8 ± 0 (1)

0

4 (4,0)

3

20.9

 18q

3.9 ± 3.3 (31)

1

4.9 ± 3.0 (6)

0

2 (2,0)

16

12.3

 19q

5.1 ± 5.4 (31)

0

2.6 ± 2.3 (2)

0

1 (1,0)

6

20.5

 20q

1.6 ± 3.2 (12)

3

1.3 ± 1.3 (17)

1

12 (8,4)

59

16.5

 21q

4.1 ± 3.8 (28)

0

5.1 ± 2.4 (4)

0

3 (3,0)

11

15.3

 22q

INP

 

INP

    

Xq/Yq

1.2 ± 1.9 (16)

3

2.6 ± 1.3 (4)

0

3 (3,0)

20

7.5

Total

780

38

82

5

92 (87,5)

11

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