Fig. 2
From: SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells
Assessment of SOX10-associated transcription start sites in differentiating primary Schwann cells. a Expression profiles of TSSs associated with SOX10-bound promoters in sciatic nerve, measured in control- and cAMP-treated primary Schwann cells. Upregulated by cAMP (yellow), downregulated by cAMP (orange), unchanged (green), or not expressed in either condition (black). b In vivo expression levels of TSS classes (as in panel a). X-axis: log10 transformed average expression level (reads per million, RPM). Y-axis: the cumulative fraction of TSSs. Asterisk indicates p < 0.03. c Per-sample expression levels for TSSs associated with enriched gene ontology terms among TSSs that are upregulated (left) and downregulated (right) upon cAMP treatment. Expression values are scaled per TSS (Z-score)