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Table 3 Standard diversity indices and global-selection at individual genes and at sub-region-level

From: Genetic diversity, evolution and selection in the major histocompatibility complex DRB and DQB loci in the family Equidae

Locus/sub-region

Length (bp)

N

VNP

PIP

Z-test

    

p-value

dN-dS

DQB1 locus

269

17

99

68

0.033

1.856

DQB2 locus

269

19

92

46

0.062

1.550

DQB3 locus

269

14

13

3

1.000

−0.610

DQB2-like sequence

269

9

32

24

1.000

−0.156

DQB sub-region

269

59

141

104

0.042

1.747

DRB1 locus

260

16

93

67

1.000

−0.303

DRB2 locus

260

20

63

37

0.157

1.012

DRB3 locus

260

15

40

11

1.000

−0.204

DRB sub-region

260

52

114

84

0.375

0.318

  1. N numbers of sequences, VNP variable nucleotide positions, PIP parsimony informative positions. Z-test p-value: probability of rejecting the null hypothesis of strict-neutrality (dN = dS) in favor of dN > dS. Significant p-values are in bold