Fig. 7From: Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infectionPathway enrichment of differentially expressed genes in the fetal thymus. A) low viral load with viable (LVL-VIA) contrasted to control (CTRL) fetuses. B) LVL with meconium staining (LVL-MEC) contrasted to CTRL fetuses. C) high viral load with viable (HVL-VIA) contrasted to CTRL fetuses. D) HVL with meconium staining (HVL-MEC) contrasted to CTRL fetuses. E) Virus positive fetus aka V + F (LVL-VIA, LVL-MEC, HVL-VIA, and HVL-MEC) contrasted to virus negative fetus V - F [UNINF, placenta only with VIA (PLCO-VIA), and PLCO-MEC]. F) Meconium stained fetus aka MEC + F (PLCO-MEC, LVL-MEC, and HVL-MEC) contrasted to viable fetus aka MEC - F (UNINF, PLCO-VIA, LVL-VIA, and HVL-VIA). The percent enrichment was calculated as the [(number of DEG assigned to a given pathway by IPA + the number of DEG manually assigned)/(total number of genes assayed on the NanoString in the given pathway)*100]. The pathway analysis plotted with pathway name on the y axis, enrichment (%) on the x, bubble size as the total number of DEG in each pathway, and the color as the IPA predicted activation Z score with blue deactivated and red activatedBack to article page