Table 2 Top five canonical pathways assembled from targets of differentially expressed sperm-borne miRNAs in two-cell embryos
From: Sperm miRNAs— potential mediators of bull age and early embryo development
10 VS 16 months | 12 VS 16 months | ||||
|---|---|---|---|---|---|
Canonical Pathways | -log(p-value) | z-score | Canonical Pathways | -log(p-value) | z-score |
TGF-β Signaling | 11.4 | 4.95 | PI3K/AKT Signaling | 10.1 | 2.402 |
Signaling by Rho Family GTPases | 10.8 | 6.565 | PTEN Signaling | 7.39 | −3.43 |
Huntington’s Disease Signaling | 10.1 | 2.333 | Insulin Receptor Signaling | 6.67 | 2 |
IGF-1 Signaling | 9.59 | 4.226 | IGF-1 Signaling | 6.31 | 3.266 |
Cardiac Hypertrophy Signaling | 9.13 | 5.515 | AMPK Signaling | 6.21 | 2.596 |