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Table 2 Gene-specific transcriptional regulators and kinase modulators in the occluded middle cerebral arteries (MCAs) from female rats. Overview of the differentially expressed genes, annotated to a subontology of the overrepresented gene-specific transcriptional regulator (PC00264) and kinase modulator (PC00140) PANTHER protein classes, in the occluded MCAs compared with control MCAs

From: Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats – comparisons with males

Gene symbol

Gene description

P-value

Fold change

PC00056: Basic Leucine Zipper Transcription Factor

Fosl1

Fos-like antigen 1

0.002

7.55

JunB

Jun B proto-oncogene

1.17E-07

4.56

Fos

FBJ osteosarcoma oncogene

0.006

2.85

Maff

V-maf musculoaponeurotic fibrosarcoma oncogene homolog F

6.65E-05

2.38

Cebpb

CCAAT/enhancer binding protein (C/EBP), beta

8.87E-05

2.08

Mafk

V-maf musculoaponeurotic fibrosarcoma oncogene homolog K

3.20E-05

1.79

Cebpg

CCAAT/enhancer binding protein (C/EBP), gamma

4.94E-05

1.71

Nfe2l2

Nuclear factor, erythroid derived 2, like 2

5.92E-05

1.55

Jdp2

Jun dimerization protein 2

1.26E-04

1.37

Batf3

Basic leucine zipper transcription factor, ATF-like 3

2.04E-04

1.31

PC00140: Kinase Modulator

Socs3

Suppressor of cytokine signaling 3

4.68E-05

11.48

Cish

Cytokine inducible SH2-containing protein

6.03E-06

2.23

Socs2

Suppressor of cytokine signaling 2

0.002

2.22

Ccnl1

Cyclin L1

5.06E-04

2.05

Pik3r1

Phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

1.97E-05

1.98

Mob3a

MOB kinase activator 3A

3.38E-04

1.91

Ccnh

Cyclin H

1.11E-04

1.50

Pkig

Protein kinase inhibitor, gamma

2.64E-04

1.45

Socs5

Suppressor of cytokine signaling 5

1.49E-05

1.35

Prkag1

Protein kinase, AMP-activated, gamma 1 non-catalytic subunit

1.05E-04

−1.28

Phka1

Phosphorylase kinase, alpha 1

8.80E-04

−1.52

Pik3r2

Phosphoinositide-3-kinase, regulatory subunit 2 (beta)

2.05E-05

−1.60

Mob2

MOB kinase activator 2

7.56E-04

−2.48