Fig. 2
From: Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function
Meta-Apo significantly reduces the derivation of functional profile between WGS and amplicon sample pairs from Dataset 1. a The Bray-Curtis distances between WGS:16S amplicon pairs (without calibration, orange bar) are higher than those of the WGS within-body-site distance (distances among WGS samples of the same body site, blue bar). b The Bray-Curtis distances between calibrated amplicon samples and their paired WGS samples become stable when using only 15 training pairs, which is significantly lower than the within-group distances of WGS. Two panels share the x-axis. The p-values were calculated by two-tail Wilcox tests, ** denotes p < 0.05 and *** denotes p < 0.01