Table 2 The functional enrichment of common “sKLD-signaling genes” in the critical stage samples for LUSC
From: Identifying critical state of complex diseases by single-sample Kullback–Leibler divergence
Gene Ontology Consortium | IPA | ||
|---|---|---|---|
enriched biological process | enriched p value | enriched biological process | enriched p value |
cytoskeleton organization (GO:0007010) | 2.00E-12 | mitosis of tumor cell lines | 1.39E-39 |
chromosome condensation (GO:0030261) | 4.49E-09 | development of malignant tumor | 6.37E-29 |
regulation of cell division (GO:0051302) | 1.23E-08 | lung squamous cell carcinoma | 1.62E-24 |
sister chromatid cohesion (GO:0007062) | 2.43E-06 | lung carcinoma | 7.28E-22 |
isotype switching (GO:0045190) | 1.03E-04 | respiratory system tumor | 1.19E-19 |
programmed cell death (GO:0012501) | 6.57E-04 | lymphocytic neoplasm | 9.89E-12 |