Fig. 5

Structural features of the GG[D/E]EF and GG[D/E]EF-EAL domains from the M. aeruginosa NIES843 genome. The domain of NIES843 is labeled in white, and the templates are labeled in light blue. The WebLogo sequence in multiple colors represents conserved motifs from M. aeruginosa strains in corresponding domains. Magnifications show the structure of GG[D/E]EF, RXXD, and EAL motifs. (a) GG[D/E]EF domain structures from the M. aeruginosa NIES843 genome. Left, GGEEF domain using the crystal structure of WspR (PDB id: 3BRE) from P. aeruginosa as the template. Right, GG[D/E]EF domain in a hybrid protein and RmcA (PDB id: 5M3C) from P. aeruginosa as the template. The RXXD and GG[D/E]EF motifs are labeled in yellow and purple, respectively. (b) Domain structures of the EAL domain in hybrid protein from the M. aeruginosa NIES843 genome. RmcA (PDB id: 5M3C) from P. aeruginosa was used as the template. The EAL signature motif is labeled in blue. (c) Structures of the HD-GYP domain of the M. aeruginosa NIES843. PA4781 (PDB id: 4R8Z) from P. aeruginosa was used as the template. The GYP loop signature motif is labeled in green