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Fig. 3 | BMC Genomics

Fig. 3

From: Genome-wide association and transcriptome studies identify candidate genes and pathways for feed conversion ratio in pigs

Fig. 3

Theoretical models of the functional actions of candidate genes in modulating the feed conversion ratio. a TPH2 regulates intestinal motility by serotonergic synapses and the oxytocin signalling pathway in the hypothalamus. TPH2 produces 5-HT, and 5-HT transmits signals to oxytocin neurons through serotonergic synapses and subsequently regulates intestinal peristalsis under the action of the oxytocin signalling pathway. b GRIP1, FRS2, CNOT2, and TRHDE genes regulate metabolism in various tissues by the thyroid hormone signalling pathway. First, GRIP1, FRS2, CNOT2 and TRHDE regulate the thyroid signalling pathway in the hypothalamus, and subsequently, the thyroid signalling pathway participates in regulating the metabolism in skeletal muscle, liver and fat. c GRIP1 regulates appetite by glutamatergic and GABAergic signalling

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BMC Genomics

ISSN: 1471-2164

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