Table 2 Gene Functional Classification Result (PANTHER 14.1) of under-expressed genes in ST cells from SNEB animals. Main pathways and ontology annotation groups enriched are shown (over-representation statistical test)

 Antiviral mechanism by IFN-stimulated genes (R-BTA-1169410)

24.99

4.03E-05

MX2 PTPN2, JAK1, DDX58, EIF2AK2, IFIT1, ISG15, STAT1

 Interferon Signaling (R-BTA-913531)

14.9

9.55E-05

 defense response to virus (GO:0051607)

19.04

3.92E-03

MX2, OAS1Y, IFIT1, OAS1Z, MX2, MX1

 Wnt signaling pathway (GO:0016055)

6.07

1.55E-02

SFRP4, APCDD1, LEF1, TLE4, SULF1, WNT6, DKK3, NID1

 Regulation of IFNG signaling (R-BTA-877312)

–

–

RAPGEF1, MX1, EIF2AK2, UBA7, ISG15, PTPN2, MX2, DDX58, IL1RAP, IL16, CRK, IFIT1, STAT1, IFNGR2, JAK1, STX3, NFATC1, ALOX12

 Cytokine Signaling in Immune system (R-BTA-1280215)

–

–

 Antiviral mechanism by IFN-stimulated genes (R-BTA-1169410)

–

–

 Extracellular matrix organisation (R-BTA-1474244)

–

–

KLK1, TPSB1, COL4A4, COL2A1, MMP19, NID1, COL6A6, COL4A3, COL26A1

 Collagen chain trimerization (R-BTA-8948216)

–

–

 Wnt signaling pathway (P00057)

–

–

CDH11, TLE4, LEF1, NFATC1, PRKCH, SMARCD2, FBXW7)

 Integrin signaling pathway (P00034)

–

–

ITGA5, ITGA10, RAPGEF1, MAP 3 K5,CRK

 Cadherin signaling pathway (P00012)

–

–

CDH11, LEF1, CDH12, CDH2, WNT6, WNT4

 Apoptosis signaling pathway (P00006)

–

–

EIF2AK2, RIPK1, PRKCH, MAP 3 K5