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Table 2 List of blood genes retained as very important to classify pigs for RFI1

From: Analysis of merged whole blood transcriptomic datasets to identify circulating molecular biomarkers of feed efficiency in growing pigs

Probe name

Gene symbol

Full name

Score

A_72_P304024

PSEN1

presenilin 1

100

A_72_P008221

SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium der

87.7

A_72_P047696

TMEM63B

transmembrane protein 63B

60.8

A_72_P035801

EPAS1

endothelial PAS domain protein 1

59.9

A_72_P010326

MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mous

59.2

A_72_P359418

WDHD1

WD repeat and HMG-box DNA binding protein 1

57.4

A_72_P418319

HTRA1

HtrA serine peptidase 1

56.2

A_72_P201717

NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide rec

56.1

A_72_P061216

ADAM9

ADAM metallopeptidase domain 9

54.5

A_72_P548816

HMG20A

high mobility group 20A

51.9

A_72_P035056

BCO2

beta-carotene oxygenase 2

50.7

A_72_P183616

TEX2

testis expressed 2

50.1

A_72_P039066

EIF1B

eukaryotic translation initiation factor 1B

48.4

A_72_P036051

GPX3

glutathione peroxidase 3 (plasma)

47.0

A_72_P131741

SLC46A3

solute carrier family 46, member 3

46.2

O12841

PARVG

parvin, gamma

42.8

A_72_P001891

SPTLC2

serine palmitoyltransferase, long chain base subunit 2

42.5

A_72_P250342

RPS18

ribosomal protein S18

40.8

O8712

ENO3

enolase 3 (beta, muscle)

39.7

A_72_P094676

UGCG

UDP-glucose ceramide glucosyltransferase

39.2

A_72_P051041

MKI67

antigen identified by monoclonal antibody Ki-67

38.6

A_72_P128591

SCML1

sex comb on midleg-like 1 (Drosophila)

38.5

A_72_P002751

JPH4

junctophilin 4

38.3

A_72_P200892

ZNF672

zinc finger protein 672

33.1

A_72_P177616

DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

32.6

A_72_P619999

OAZ3

ornithine decarboxylase antizyme 3

32.3

A_72_P134026

NUP43

nucleoporin 43 kDa

30.2

A_72_P126346

WBSCR27

Williams Beuren syndrome chromosome region 27

30.1

A_72_P000776

PAG1

phosphoprotein associated with glycosphingolipid microdomains 1

29.7

A_72_P185296

CLU

Clusterin

29.3

A_72_P289839

ZNF3

zinc finger protein 3

27.4

A_72_P470830

ORC4

origin recognition complex, subunit 4

27.4

A_72_P000506

CREBRF

CREB3 regulatory factor

27.9

A_72_P499239

TSPAN7

tetraspanin 7

16.3

  1. 1A gradient tree boosting (GTB) algorithm was applied on transcriptomic dataset (26,687 annotated molecular probes) from the whole blood of 148 growing pigs. Data were split into training (n = 74) and validation test (n = 74) subsets to evaluate model performance in classifying pigs into low or high residual feed intake (RFI) groups. The unique genes corresponding to the most relevant annotated probes able to attribute RFI class for each pig were listed. The score attributed to each probe gave hierarchy of importance in the predictive model