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Table 5 Logistic regression analysis of the association between cg04481923 methylation level in VTRNA2-1 gene and preterm births (n = 82)

From: Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth

Methylation

β-value

SE

Odds ratio

95 % CI

p-value

Age

-0.057

0.035

0.945

0.882–1.012

0.104

Season

-0.582

0.238

0.559

0.350–0.892

0.015

Parity

0.389

0.313

1.475

0.798–2.727

0.215

VTRNA2-1a

1.185

0.574

3.269

1.061–10.069

0.039

WBC count

0.211

0.075

1.235

1.066–1.431

0.005

  1. β-values and SE estimated using the multivariable logistic regression model
  2. VTRNA2-1 vault RNA 2 − 1
  3. aIt was divided into two groups based on the methylation level of VTRNA2-1 promoter: a hypomethylated group (< 13 %, n = 28) and an elevated methylated group (30–60 %, n = 54)
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BMC Genomics

ISSN: 1471-2164

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