Table 2 When combined with different similarity matrices, the proposed model is evaluated via 5-fold CV based on the disease-based group preference
Combined similarity matrices | 5-fold CV |
|---|---|
No integrated similarity of microbe or disease via Eq. (18) | 0.6169+/− 0.0561 |
Disease semantic similarity | 0.6796+/−0.0468 |
Microbe sequence similarity and microbe evolutionary distance-based similarity | 0.7171+/−0.0427 |
Disease semantic similarity, microbe sequence similarity and microbe evolutionary distance-based similarity | 0.8081+/−0.0284 |