Fig. 4
From: Transcriptomic profiling implicates PAF1 in both active and repressive immune regulatory networks
PAF1 KO shows increased expression of virus host-dependency factors. GSEA was performed on gene expression data from PAF1 KO relative to ncgRNA for each stimulation using custom gene sets describing host-dependency factors for various viruses. Colors indicate stimuli type and transparency indicates adjusted p-values for each test. AÂ NES values are plotted with error bars representing log2 of the expected error for the standard deviation of the P-value logarithm. The size of each gene set is provided in parentheses. GSEA random walks as summarized in (A) are shown for Flaviviruses (B), Influenza A Virus (C), HIV (D), and SARS-CoV-2 (E)