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Fig. 5 | BMC Genomics

Fig. 5

From: Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival

Fig. 5

Inhibition of miR-24-3p increases apoptosis in HCT116 cells. A MiR-24-3p expression from RT-qPCR following mock, 100 nM scramble, or 100 nM miR-24 inhibitor treatment of HCT116 cells. Significance determined by two-tailed Student’s t-test. Cell count (B), CellTiter-glo (C), EdU incorporation (D), and TUNEL (E) assays following mock, 100 nM scramble, or 100 nM miR-24 inhibitor treatment in HCT116 cells. Signficance determined by two-sided Wilcoxon test. Results reported relative to average mock control. Color of data points represents experimental replicate. *p < 0.05, **p < 0.01, ***p < 0.001

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