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Fig. 5 | BMC Genomics

Fig. 5

From: Genome-wide differential DNA methylation analysis of MDA-MB-231 breast cancer cells treated with curcumin derivatives, ST08 and ST09

Fig. 5

Changes in ST08 and ST09-mediated DNA methylation modification correlate with gene expression changes. We performed genome-wide gene expression analyses to evaluate if ST08 and ST09-mediated DNA methylation changes correlated with gene expression variation. Genes that showed reproducible DNA methylation changes after ST08 (A), and ST09 (B) treatment (Δβ > 0.1) were matched with genes that showed ≥ 1-fold differences in gene expression. Those genes that showed an inverse correlation between methylation and gene expression changes are encircled in the graph

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BMC Genomics

ISSN: 1471-2164

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