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Fig. 1 | BMC Genomics

Fig. 1

From: Identification and characterization of non-coding RNA networks in infected macrophages revealing the pathogenesis of F. nucleatum-associated diseases

Fig. 1

Analysis of differentially expressed mRNAs. A Cell viability of dTHP-1 cells were measured by MTT assay after infection with F. nucleatum at the indicated MOI (0, 10,100, 200 and 500) for 24 h or 48 h. The one-way ANOVA with Tukey’s post hoc Tests, ***P < 0.001, vs control group (MOI = 0). B Volcano plot depicting mRNAs. Gray dots represent RNAs not significantly differentially expressed (Padj > 0.05) and the other dots represent RNAs differentially expressed (Padj < 0.05). C Hierarchical cluster analysis of the differential mRNA expression profile. Yellow and blue represented increased and decreased expression, respectively. Each sample was indicated by a single column, and each RNA was denoted by a single row of colored boxes. D GO analysis results for the differentially expressed mRNAs (DEGs). E KEGG analysis for differentially expressed mRNAs (DEGs). F Top 8 KEGG pathways that the up-regulated and down-regulated genes involved in, respectively. G KEGG DISEASE analysis for differentially expressed mRNAs (DEGs)

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BMC Genomics

ISSN: 1471-2164

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