Table 3 Significantly enriched KEGG and InterPro terms of DAVID functional annotation in temporal expressional change

 ame00010: Glycolysis / Gluconeogenesis

20

12

9

11

1

 ame00030: Pentose phosphate pathway

11

6

6

5

1

 ame00260: Glycine, serine and threonine metabolism

8

10

2

6

4

 ame00520: Amino sugar and nucleotide sugar metabolism

15

–

15

–

–

 ame00561: Glycerolipid metabolism

14

9

5

9

0

 ame00620: Pyruvate metabolism

12

11

3

9

2

 ame00670: One carbon pool by folate

7

5

2

5

0

 ame01100: Metabolic pathways

154

109

70

84

25

 ame01130: Biosynthesis of antibiotics

52

40

19

33

7

 ame01200: Carbon metabolism

31

21

15

16

5

 ame01230: Biosynthesis of amino acids

25

17

10

15

2

 ame04142: Lysosome

19

14

9

10

4

 ame04512: ECM-receptor interaction

9

–

9

–

–

 IPR000618:Insect cuticle protein

25

23

3

22

1

 IPR001071:Cellular retinaldehyde binding/alpha-tocopherol transport

6

8

0

6

2

 IPR001251:CRAL-TRIO domain

–

10

–

–

10

 IPR001254:Peptidase S1

11

13

2

9

4

 IPR001436:Alpha crystallin/Heat shock protein

7

9

0

7

2

 IPR001507:Zona pellucida domain

–

8

–

–

8

 IPR002557:Chitin binding domain

21

18

5

16

2

 IPR005828:General substrate transporter

20

16

8

12

4

 IPR006631:Protein of unknown function DM4/12

9

10

0

9

1

 IPR009003:Trypsin-like cysteine/serine peptidase domain

11

13

2

9

4

 IPR011074:CRAL/TRIO, N-terminal domain

7

9

0

7

2

 IPR012132:Glucose-methanol-choline oxidoreductase

11

8

5

6

2

 IPR012464:Protein of unknown function DUF1676

–

12

–

–

12

 IPR020846:Major facilitator superfamily domain

47

33

21

26

7