Table 3 Genes with functional significance identified in the selection peaks and flanking regions in the Asian versus European horse cohorts
ECA | Region (Mb) | CSS value | Candidate genes | Function |
|---|---|---|---|---|
3 | 34.7–36.22 | 2.59 | APRT | Lactation, grooming behaviour |
CA5A, CTU2, MAP1LC3B, SPG7, ACSF3, CYBA | Mitochondria | |||
CYBA, IL17C, APRT | Inflammatory response | |||
GALNS, IL17C | Innate immune system | |||
JPH3, KLHDC4, SNAI3 | Motor coordination | |||
MVD | Metabolic pathways | |||
SLC7A5, SPG7 | Nervous system development | |||
ZFPM1, TCF25, FOXL1, FOXF1, FOXC2, DBNDD1 | Heart development | |||
MC1R | Pigmentation | |||
GAS8, FANCA | Sperm motility, gonad development | |||
CDH15, ANKRD11 | Intellectual disability |