Fig. 3

Comparisons between REDfly and EnhancerAtlas enhancer sets. REDfly and EnhancerAtlas datasets were compared and tested for significance as described in the text and TableS1 [Additional File 1]. Box plots show medians and the first and third quartiles. Data points shown in red are significant at a Bonferonni-adjusted P-value < 0.01. Dataset names correspond to the names in Table S1 [Additional File 1]. For the “tissue-specific comparisons” (Table S1c [Additional File 1]), when multiple REDfly sets corresponded to the same EnhancerAtlas set, the one with the highest degree of overlap was selected for analysis. For the subset comparisons (Table S1d,e [Additional File 1]), the REDfly set with the largest number of significantly overlapping individual EnhancerAtlas component sets was used. A z-score distributions for each of the REDfly-EnhancerAtlas comparisons. B Percent of REDfly enhancers found that overlap EnhancerAtlas enhancers. For the “all tissue-specific datasets” plot, datasets with significant z-scores are indicated in red. For the subset comparisons, values represent the median percent overlap of the constituent data subsets, as shown in Table S1e [Additional File 1]