Fig. 3
From: Evaluating histone modification analysis of individual preimplantation embryos
Simultaneous profiling of H3K4me3 and H3K27ac within the same blastocysts assessed by WOW-CAT. a The results were similar to those reported by Zhou et al. [16] in terms of the common (unshaded), H3K4me3-dominant (blue-shaded), and H3K27ac-dominant (red-shaded) areas, respectively. Blastocyst icon is from Biorender.com. b, c Heatmap and volcano plot, respectively, of the normalized H3K4me3 and H3K27ac modifications within three single blastocysts. d Examples of H3K4me3- and H3K27ac-dominant genes. e Gene Ontology terms enriched by H3K4me3- and H3K27ac-dominant genes