Table 1 Pseudogenome and functional genome characteristics of African and PA38 MU strains
From: Pseudogenomic insights into the evolution of Mycobacterium ulcerans
Genome characteristics | African isolates | PA38 |
|---|---|---|
Genome reduction | Yes | Yes |
Expanded genome | No | Yes |
Decrease in gene-coding capacity | Yes | Yes |
Increased IS elements | No | Yes |
Decreased purifying selection | No | Yes |
Increased pseudogenes levels | Yes | Yes |
Further genome erosion | Yes | No |
Loss of mobilome (IS elements) | Yes | No |
Increased purifying selection | Yes | No |