Fig. 2
From: Sex-biased genetic regulation of inflammatory proteins in the Dutch population
Summary of pQTL meta-analysis results in males. A Manhattan plot depicting the association results of significant genetic variants (P < 0.05). The red bold horizontal line marks the genome-wide significant threshold (p-value < 1 × 10–8) and the black dashed denotes the suggestive threshold (p-value = 5 × 10–5). Top pQTL variants and their correlated proteins are displayed on the plot. B Regional association plots of the genome-wide significant loci (p < 1 × 10–8). The -log10 association p-values are plotted on the y-axis against physical position (NCBI build 36) of each marker on the x-axis. The pQTL variants are color coded according to their correlation coefficient (r2) with the top SNP using the hg19/1000 Genomes European samples