Unified mRNA Subcellular Localization Predictor based on machine learning techniques

BMC Genomics

Table 4 ML model results based on PCA

Model/Class	Pr	Sn	Acc	Sp	F1
CatBoost
Cytoplasm	0.73	0.87	0.81	0.76	0.79
ER	0.94	0.36	0.94	1.00	0.52
ExR	0.78	0.16	0.95	1.00	0.27
Mitochondria	0.98	0.86	1.00	1.00	0.91
Nucleus	0.80	0.85	0.86	0.86	0.82
Avg	0.84	0.62	0.91	0.92	0.66
XGBoost
Cytoplasm	0.73	0.87	0.81	0.76	0.80
Er	0.91	0.38	0.94	1.00	0.54
ExR	0.78	0.16	0.95	1.00	0.26
Mitochondria	0.95	0.85	0.99	1.00	0.90
Nucleus	0.81	0.85	0.86	0.87	0.83
Avg	0.83	0.62	0.91	0.92	0.66
Decision Tree
Cytoplasm	0.66	0.65	0.71	0.75	0.65
ER	0.31	0.35	0.86	0.92	0.33
ExR	0.16	0.16	0.91	0.95	0.16
Mitochondria	0.75	0.64	0.98	0.99	0.69
Nucleus	0.68	0.69	0.75	0.80	0.68
Avg	0.51	0.50	0.84	0.88	0.50
GNB
Cytoplasm	0.63	0.20	0.61	0.91	0.30
Er	0.18	0.55	0.71	0.73	0.27
ExR	0.16	0.34	0.86	0.90	0.22
Mitochondria	0.42	0.95	0.96	0.96	0.58
Nucleus	0.59	0.58	0.68	0.74	0.59
Avg	0.40	0.52	0.76	0.85	0.39
MLP
Cytoplasm	0.76	0.79	0.80	0.81	0.77
ER	0.62	0.54	0.92	0.97	0.58
ExR	0.35	0.18	0.93	0.98	0.24
Mitochondria	0.93	0.81	0.99	1.00	0.87
Nucleus	0.78	0.83	0.84	0.85	0.81
Avg	0.69	0.63	0.90	0.92	0.65

ISSN: 1471-2164