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Fig. 2 | BMC Genomics

Fig. 2

From: Adrenarche-accompanied rise of adrenal sex steroid precursors prevents NAFLD in Young Female rats by converting into active androgens and inactivating hepatic Srebf1 signaling

Fig. 2

Adrenarche-accompanied rise of androgens prevents liver growth during adrenarche in young female rats. A Both flutamide (androgen receptor antagonist) and dihydrotestosterone (DHT) administration had minimal effects on body growth during adrenarche in young female rats. B Representative images of the liver of young female rats following flutamide or DHT administration. C-D Blocking androgen actions by flutamide administration across adrenarche largely increased liver weight and liver index in young female rats. NS, not significant, *** p < 0.001

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BMC Genomics

ISSN: 1471-2164

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