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Fig. 8 | BMC Genomics

Fig. 8

From: Adrenarche-accompanied rise of adrenal sex steroid precursors prevents NAFLD in Young Female rats by converting into active androgens and inactivating hepatic Srebf1 signaling

Fig. 8

Formestane administration during adrenarche had minimal effects on liver lipogenesis and lipid deposition in young female rats. Formestane (FMT) administration across adrenarche exerted minimal effects on body weight A, liver weight (B) and liver index (C) in young female rats. (D) Representative images of the liver section stained with Oil Red O (×20 magnification). (E) mRNA expression of key lipogenic genes in liver of young female rats administrated with formestane (FMT) or vehicle. F Expression of key genes mediating the conversion of DHEA into both active androgens and estrogens as well as sex hormone receptor encoding genes in liver of young female rats

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BMC Genomics

ISSN: 1471-2164

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